Effects of osteoblast-derived extracellular vesicles on aggressiveness, redox status and mitochondrial bioenergetics of MNNG/HOS osteosarcoma cells.

Front Oncol · 2022 · PMC9762506 · PMID 36544705

Europe PMC DOI

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0.0510

closest p · 1.0× alpha

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boldest claim

The sentences

almost significantp=0.051so close (0.05 < p ≤ 0.1)

Although OB-EVs did not change the glycolytic/OxPhos ATP ratio, MitoStress experiments revealed an almost significant trend (p=0.051) of reduction in basal respiration, and a reduction in maximal respiration and spare respiratory capacity in 3 over 4 experiments analysed in OB-EVs-treated cells.

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a strong trendp=0.051so close (0.05 < p ≤ 0.1)

However, mitostress assays showed a strong trend of reduction in basal respiration (BR, p=0.051), with non-significant reductions in maximal respiratory capacity (MRC) and spare respiratory capacity (SRC, Figure 3C ) following OB-EVs treatment.

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