Finally, patients triple mutated for NPM1, FLT3, and DNMT3A (n=10) had a 1-year cumulative incidence of relapse of 50% as compared to 25.9% in others, but the difference did not reach statistical significance (p=0.07).
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Pre-transplant gene profiling characterization by next-generation DNA sequencing might predict relapse occurrence after hematopoietic stem cell transplantation in patients affected by AML.
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