Plasma apixaban levels in Chinese patients with chronic kidney disease-Relationship with renal function and bleeding complications.

Front Pharmacol · 2022 · PMC9772439 · PMID 36569289

Europe PMC DOI

hedged sentence

0.0590

closest p · 1.2× alpha

0.0590

boldest claim

The sentences

did not reach statistical significancep = 0.059so close (0.05 < p ≤ 0.1)

Patients with stage 4 CKD presented numerically higher mean peak plasma apixaban levels than those with stage 3 or 2 CKD, although this result did not reach statistical significance (peak level: 147.6 ± 35.1 ng/ml ng/ml vs. 122.9 ± 55.5 ng/ml vs. 70.5 ng/ml; p = 0.059) ( Figures 4A,B ).

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