A recent pan-cancer validation study again found an overall effect on time to first recurrence but the subgroup of HNSCC demonstrated a small effect size and did not reach statistical significance (HR = 0.99, CI [0.96–1.01]) [ 47 ].
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Prognostic and Predictive Biomarkers in Head and Neck Squamous Cell Carcinoma Treated with Radiotherapy-A Systematic Review.
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