Prostacyclin Released by Cancer-Associated Fibroblasts Promotes Immunosuppressive and Pro-Metastatic Macrophage Polarization in the Ovarian Cancer Microenvironment.

Cancers (Basel) · 2022 · PMC9776493 · PMID 36551640

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did not reach statistical significanceno p-value reported

Addition of the PTGIR antagonist CAY10449 reduced the MRE-269-mediated cAMP accumulation in 4 of 6 samples ( Figure 3 E), but did not reach statistical significance due to high donor-specific variability.

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