Moreover, febuxostat is slightly superior to allopurinol in lowering the decline in eGFR and the increase in proteinuria, but the difference did not reach statistical significance [ 66 ].
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Prevalence and Predictors of Renal Disease in a National Representative Sample of the Romanian Adult Population: Data from the SEPHAR IV Survey.
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The SEPHAR III survey was conducted in 2016 and revealed an increasing trend in the prevalence of DM (17.8%), obesity (47%), and dyslipidemia (83.2%) with subclinically and clinically overt target organ damage (TOD) as follows: albuminuria 30–300 mg/g in 4.9%, albuminuria > 300 mg/g in 2.2%, eGFR: 30–60 mL/min/1.73 m 2 in 4.6%, eGFR < 30 mL/min/1.73 m 2 in 0.7%, heart failure (HF) in 15.3%, coronary artery disease (CAD) in 32.1%, atrial fibrillation (AF) in 8.1%, stroke in 5.1%, peripheric arterial diseases (PAD) in 3.7%, and carotid plaques in 22.5%.