Population pharmacokinetics of liposomal amphotericin B in adults with HIV-associated cryptococcal meningoencephalitis.

J Antimicrob Chemother · 2022 · PMC9780527 · PMID 36411251

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did not reach statistical significanceno p-value reported

The inclusion of dose and baseline fungal burden as modifying variables had the effect of reducing τ 2 from 0.0023 to 0.0003, indicating a trend towards reduction in total inter-study heterogeneity; however, this did not reach statistical significance ( P value for moderators, 0.28).

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