Cryptococcal Immune Reconstitution Inflammatory Syndrome: From Clinical Studies to Animal Experiments.

Microorganisms · 2022 · PMC9780901 · PMID 36557672

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did not reach statistical significanceno p-value reported

Interestingly, the expression of anti-inflammatory cytokine IL-10 was also enhanced in IRIS patients compared to non-IRIS patients, although the difference did not reach statistical significance; there was a significant correlation between IL-10, IL-6, and IFN-γ, suggesting that the excessive inflammation that characterizes IRIS occurs first, followed by a compensatory secretion of IL-10 [ 79 ].

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