Antiplatelet Therapy Aims and Strategies in Asian Patients with Acute Coronary Syndrome or Stable Coronary Artery Disease.

J Clin Med · 2022 · PMC9784545 · PMID 36556067

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

did not reach statistical significancep = 0.06so close (0.05 < p ≤ 0.1)

In a primary analysis of 1,849 CYP2C19 LOF carriers, composite CV death, MI, stroke, stent thrombosis, and severe recurrent ischemia occurred in 4.0% (35/903) and 5.9% (54/946) of patients in the genotype-guided and conventional arms, respectively, but the difference did not reach statistical significance ( p = 0.06).

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a decreasing trendno p-value reported

Although there are some suggestions of a decreasing trend in recurrent coronary hospitalization in recent years [ 16 ], the risk remains high, especially for patients with additional risk factors [ 17 ].

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