Barely Significant
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Psychological stress induces moderate pathology in the ganglion cell layer in mice.

Mol Vis · 2022 · PMC9784625 · PMID 36605831

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a clear trendno p-value reported
Over the past decade, a clear trend has been observed in Chinese glaucoma clinics, where an increased number of young patients in their 20s to 40s are diagnosed with POAG.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.