In addition to generating more potent antibody responses and dominant Th1 responses, immunization with Pam3.GM2 also yielded a trend toward improved efficacy upon challenge with RSV, although the difference among treatment groups did not reach statistical significance ( Figure 3 C).
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Microparticle RSV Vaccines Presenting the G Protein CX3C Chemokine Motif in the Context of TLR Signaling Induce Protective Th1 Immune Responses and Prevent Pulmonary Eosinophilia Post-Challenge.
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