A Regional Observational Study on COVID-19-Associated Pulmonary Aspergillosis (CAPA) within Intensive Care Unit: Trying to Break the Mold.

Administration of immunomodulatory agents ( p = 0.061) or broad-spectrum antibiotics ( p = 0.091), positive culture for Aspergillus on BAL ( p = 0.065) and hypertension ( p = 0.083) failed to reach significance as risk factors on the overall mortality ( Table 6 ).

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However, administration of immunomodulatory agents or broad-spectrum antibiotics, positive culture for Aspergillus on BAL, and hypertension seemed to be correlated with increased mortality at 28 days from admission to the ICU, but failed to reach statistical significance, as with all the considered factors in the multivariate analysis, probably due to the limited sample size.

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