The preliminary and full results of the trials were later published and revealed that JNJ-54861911 treatment did not show any benefit over placebo, caused an elevation of liver enzymes and showed a trend towards declines in cognition with evidence of reversibility after 6 months off treatment [ 67 , 68 , 69 ].
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BACE1 Inhibitors for Alzheimer's Disease: The Past, Present and Any Future?
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