Interleukins-6 and -10 remained largely unchanged, with a reducing trend noted in interleukin-10 in CKD stage 4, and an increasing trend in interleukin-6 in CKD stage 3b.
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Markers of Oxidative Stress, Inflammation and Endothelial Function following High-Dose Intravenous Iron in Patients with Non-Dialysis-Dependent Chronic Kidney Disease-A Pooled Analysis.
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The sentences
The lack of a significant trend in pulse wave velocity and augmentation index measurements, as surrogate markers of aortic stiffness, would suggest that there is no clinically relevant impact following the administration of iron in non-dialysis-dependent CKD or atherosclerosis secondary to an increase in selectins.
The pulse wave velocity and augmentation index remained unchanged, with a decreasing trend in the pulse wave velocity noted in patients with CKD stage 3b.