Barely Significant
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Markers of Oxidative Stress, Inflammation and Endothelial Function following High-Dose Intravenous Iron in Patients with Non-Dialysis-Dependent Chronic Kidney Disease-A Pooled Analysis.

Int J Mol Sci · 2022 · PMC9787941 · PMID 36555659

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The sentences

an increasing trendno p-value reported
Interleukins-6 and -10 remained largely unchanged, with a reducing trend noted in interleukin-10 in CKD stage 4, and an increasing trend in interleukin-6 in CKD stage 3b.

also in 63,971 other papers

a significant trendno p-value reported
The lack of a significant trend in pulse wave velocity and augmentation index measurements, as surrogate markers of aortic stiffness, would suggest that there is no clinically relevant impact following the administration of iron in non-dialysis-dependent CKD or atherosclerosis secondary to an increase in selectins.

also in 9,775 other papers

a decreasing trendno p-value reported
The pulse wave velocity and augmentation index remained unchanged, with a decreasing trend in the pulse wave velocity noted in patients with CKD stage 3b.

also in 47,180 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.