Phenotypic, transcriptomic and functional profiling reveal reduced activation thresholds of CD8+ T cells in giant cell arteritis.

Rheumatology (Oxford) · 2022 · PMC9788826 · PMID 35460236

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a strong trendno p-value reported

MAIT cells, defined as CD3 + CD4 − TCRγδ − TCRVα7.2 + CD161 + , had an increased proliferative capacity in response to IL-12 and IL-18 stimulation and showed a strong trend towards increased proliferative capacity after stimulation with anti-CD3/CD28 beads [ 26 ].

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