Glycemic control releases regenerative potential of pancreatic beta cells blocked by severe hyperglycemia.

11 Treatment with dapagliflozin resulted in highly significant reduction of glucose levels (nadir 13.6 ± 1 mmol/L at 28 days of treatment).

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37 Some increase in apoptosis was suggested in our in vitro whole-islet model ( Figure 5A ) but this effect was modest at most and it did not reach statistical significance.

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