Barely Significant
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Bortezomib-induced neurotoxicity in human neurons is the consequence of nicotinamide adenine dinucleotide depletion.

Dis Model Mech · 2022 · PMC9789399 · PMID 36398590

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showed a trendno p-value reported
Although 3 nM BTZ showed a trend towards increased caspase activation, the change was not significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.