Anti-SARS-Cov-2 S-RBD IgG Formed after BNT162b2 Vaccination Can Bind C1q and Activate Complement.

In our study, bound C1q and formed C5b-9 were both higher in the PCR(+) compared to the unvaccinated group but did not reach statistical significance, probably since participants were not hospitalized and did not have an active infection at the time of sample collection.

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