Response to Article "Serum Levels of Galectin-9 are Increased in Cervical Cancer Patients and are Higher in Advanced Clinical Stages" [Response to Letter].

With respect to the studies focused on galectin-9 expression tissue, Punt et al reported that presence of galectin-9 showed a trend toward improved survival and Beyer et al reported that high expression of galectin-9 was correlated with better prognosis, so these studies are not contradictory. 2 , 3 But, the results of serum concentration of galectin-9 obtained in our study showed that serum concentration increases in advanced FIGO stages and it is not related with the level of expression in the tumor tissue; these results suggest that galectin-9 could be playing different roles in the tumor cells and in the serum.

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