Biomarker-driven prognostic models in chronic heart failure with preserved ejection fraction: the EMPEROR-Preserved trial.

Also, both albuminuria determined by urinary albumin‐to‐creatinine ratio (UACR), and Kansas City Cardiomyopathy Questionnaire overall summary score (KCCQ‐OSS) were highly significant independent predictors (each p < 0.0001), but they were excluded from our primary model because these variables are not readily available for clinical use, and also UACR was not available in our validation cohort.

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On this absolute scale there is a significant trend in treatment effect by risk groups: for low, medium, and high‐risk groups the rate differences are −0.64, −1.86 and −3.93 primary events per 100 patient‐years, respectively ( p for trend = 0.026).

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