showed a trendP < 2.63 × 10 −6
African (OR, 28.7; 95% CI, 0.6–300.6; P = 4.3 × 10 −2 ) and South Asian (OR, 32.4; 95% CI, 4.5–362.0; P = 1.7 × 10 −4 ) ancestry groups showed a trend toward enrichment that did not exceed study-wide significance ( P < 2.63 × 10 −6 accounting for ∼19,000 genes).