Blockade of dual immune checkpoint inhibitory signals with a CD47/PD-L1 bispecific antibody for cancer treatment.

A relative stable radioactivity level was maintained in the tumors (79.7% of the maximum value) at 168 h post-dose, while a decreasing trend was observed in most other organs examined.

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The average tumor-to-muscle ratio showed a trend of rising at first, followed by a decline, reaching its peak value of 11.28 at 120 h post-dose (Figure 5 B).

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