Osteopontin associates with brain T<sub>RM</sub>-cell transcriptome and compartmentalization in donors with and without multiple sclerosis.

iScience · 2023 · PMC9804143 · PMID 36594029

Europe PMC DOI

hedged sentence

0.0700

closest p · 1.4× alpha

0.0700

boldest claim

The sentences

approached significancep = 0.07so close (0.05 < p ≤ 0.1)

MS4A1 (CD20) was upregulated in CD8 + WM, CD8 + GM, and CD4 + WM versus circulating T EMRA cells, upregulated in CD8 + GM and CD4 + WM and approached significance in CD8 + WM T cells versus circulating T EM cells (adjusted p = 0.07), with substantial expression levels (44 th percentile of whole transcriptome) ( Figure S5 ).

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