RPRM deletion preserves hematopoietic regeneration by promoting EGFR-dependent DNA repair and hematopoietic stem cell proliferation post ionizing radiation.

The LSKs of female KO mice showed a trend of reduction in γ‐H2AX levels 24 h after IR compared with those of female WT mice (Figure S5A–B ), and the significantly shorter tail moment of the LSK cells of female KO mice was clearly observed at only 1 h but not 24 h after irradiation (Figure S5C–D ).

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