Trends of Rifampicin Resistance in Patients with Pulmonary Tuberculosis: A Longitudinal Analysis Based on Drug Resistance Screening in Eastern China Between 2015 and 2019.

Infect Drug Resist · 2022 · PMC9805726 · PMID 36597456

Europe PMC DOI

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an increasing trendP<0.001actually significant

An increasing trend was also identified in the rate of rifampicin and ofloxacin co-resistance (P<0.001).

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a decreasing trendP<0.001actually significant

There was a decreasing trend in the rifampicin resistance rate in both initial and re-treated patients (P<0.001), but the rifampicin resistance rate was higher in re-treated TB patients than in TB patients receiving their initial treatment (11.4% vs 4.2%).

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showed a trendno p-value reported

Conclusion This study suggests that between 2015 and 2019, the overall rifampicin resistance rate in Zhejiang Province showed a trend to decrease, and the rifampicin resistance rate in all municipalities also showed a decreasing trend.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.