Autoantibodies associated with systemic sclerosis in three autoimmune diseases imprinted by type I interferon gene dysregulation: a comparison across SLE, primary Sjögren's syndrome and systemic sclerosis.

Lupus Sci Med · 2022 · PMC9806068 · PMID 36581379

Europe PMC DOI

hedged sentences

0.0150

closest p · 0.3× alpha

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boldest claim

The sentences

borderline significantp=0.015actually significant

SLEDAI scores showed a borderline significant correlation with the number of positive SSc-associated autoantibodies (r=0.11, p=0.015).

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did not reach statistical significanceno p-value reported

Antibodies versus SLE classification criteria In SLE, presence of antibodies against CENP-B was significantly associated with serositis in the discovery cohort (p=0.005) and in both cohorts merged (p=0.007) but did not reach statistical significance in the replication cohort.

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