Ectodermal origins of the skin-brain axis: a novel model for the developing brain, inflammation, and neurodevelopmental conditions.

In line with their mouse model findings, TEWL appeared likely elevated in individuals with ASD, however, differences did not reach statistical significance in this small sample size, with adolescent-associated corneocyte flattening and heightened sebum secretion also possibly reducing the ability to discern differences between groups [ 60 ].

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