Chemically modified small interfering RNA targeting Hedgehog signaling pathway for rheumatoid arthritis therapy.

Mol Ther Nucleic Acids · 2023 · PMC9813581 · PMID 36618268

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quite significantno p-value reported

46 However, in clinical practice, whether therapies improve joint function or not is quite significant for the prognosis of RA patients. 47 , 48 Our results indicated that si-S1A3-Chol treatment alleviated functional impairment in CIA mice.

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