Multivariate effects of pH, salt, and Zn²⁺ ions on Aβ₄₀ fibrillation.

3C , we saw a clear trend of collapsing when increasing the charge of Histidine from +0.5 (black) to +2 (cyan), which is due to the increasing attractive interactions inside the N-terminal part of the chain (Fig. 3E ).

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