The "Histoplasmosis Porto Alegre manifesto"-Addressing disseminated histoplasmosis in AIDS.

PLoS Negl Trop Dis · 2023 · PMC9815569 · PMID 36602963

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This study also showed a trend to less mortality when a positive antigen detection test precedes a diagnosis by conventional methods (14.3% versus 26.9%), which corroborates the observation that in North America, where antigen detection is widely available, mortality rates of DH are significantly lower (around 10%) [ 8 , 14 ].

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