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Efficacy and Safety of First-Line Targeted Treatment and Immunotherapy for Patients with Biliary Tract Cancer: A Systematic Review and Meta-Analysis.

Cancers (Basel) · 2022 · PMC9817514 · PMID 36612035

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showed a trendno p-value reported
The trial by Chen et al., 2015 [ 34 ] showed a trend toward improved PFS was observed, but the addition of cetuximab did not significantly improve the ORR of GEMOX chemotherapy in advanced BTC, and KRAS mutations did not affect the trend in ORR and PFS differences between C-GEMOX and GEMOX.

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