Based on body composition analysis, the percentages of lean mass were comparable between the different groups whereas the percentage of fat mass was dramatically decreased in the Doxo group compared to the Ctrl group at 50 days after the first Doxo injection and consistently with the body weight results, mice treated with NMN showed a trend toward rescue in fat mass ( Supplementary Figure S2B ).
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Nicotinamide Mononucleotide Administration Prevents Doxorubicin-Induced Cardiotoxicity and Loss in Physical Activity in Mice.
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