Large Cancer Pedigree Involving Multiple Cancer Genes including Likely Digenic <i>MSH2</i> and <i>MSH6</i> Lynch Syndrome (LS) and an Instance of Recombinational Rescue from LS.

Cancers (Basel) · 2022 · PMC9818763 · PMID 36612224

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hedged sentence

0.0800

closest p · 1.6× alpha

0.0800

boldest claim

The sentences

did not reach statistical significancep = 0.08so close (0.05 < p ≤ 0.1)

The age at cancer onset among carriers of MSH6 c.3936_4001+8dup (intronic) alone versus non-carriers of either MMR variant did not reach statistical significance ( p = 0.08, Figure 3 C).

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