Novel and Off-Label Biologic Use in the Management of Hidradenitis Suppurativa, Pyoderma Gangrenosum, Lichen Planus, and Seborrheic Dermatitis: A Narrative Review.

Dermatol Ther (Heidelb) · 2023 · PMC9823183 · PMID 36434425

Europe PMC DOI

hedged sentence

0.4600

closest p · 9.2× alpha

0.4600

boldest claim

The sentences

did not reach statistical significancep = 0.46not close (p > 0.1)

Additionally, several patients reported measurable quality-of-life improvement via the Dermatology Life Quality Index (DLQI) and reduction in pain symptoms via the visual analog pain scale (VAS) at week 8 compared with baseline, although the difference did not reach statistical significance (DLQI, mean difference = 8.0; p = 0.46; VAS, mean difference = 1.2, p = 0.64) [ 18 ].

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