Ethinylestradiol in combined hormonal contraceptive has a broader effect on serum proteome compared with estradiol valerate: a randomized controlled trial.

Hum Reprod · 2023 · PMC9825269 · PMID 36416543

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did not reach statistical significanceno p-value reported

In the same study, EE + DRSP also increased CRP, although the difference compared to E4 + DRSP did not reach statistical significance ( Klipping et al. , 2021 ).

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