which implements Welch’s t -test [ 32 ] to categorize the associations into one of three groups: (i) concordant effect direction (CED) defined, for effects sizes in the same direction, as association that is significant at P FDR < 0.05 in one fetal sex and at least nominally significant in the other fetal sex; (ii) single sex effect (SSE) when significant association is present in one fetal sex ( P FDR < 0.05) and no association observed in the other fetal sex; or (iii) opposite effect direction (OED) defined, for effect sizes in opposite direction, as association that is significant in one fetal sex ( P FDR < 0.05) and at least nominally significant in the other fetal sex.
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Prenatal social support in low-risk pregnancy shapes placental epigenome.
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