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Achieving higher efficacy without compromising safety with factor XI inhibitors versus low molecular weight heparin for the prevention of venous thromboembolism in major orthopedic surgery-Systematic review and meta-analysis.

J Thromb Haemost · 2022 · PMC9828034 · PMID 36128769

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In the sensitivity analysis comparing the relative benefit of more effective dosages of FXI to LMWH, the reduction in major or CRNM bleeding events was 39% but did not reach statistical significance.

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