Early initiation of riluzole may improve absolute survival in amyotrophic lateral sclerosis.

Muscle Nerve · 2022 · PMC9828202 · PMID 36117390

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did not reach statistical significanceno p-value reported

In multivariable Cox proportional hazard models that included age, sex, and onset site (bulbar or non‐bulbar), ALSFRS, TFOE and riluzole, riluzole*TFOE interactions did not reach statistical significance, and did not offer better concordance (c‐statistic) compared to the base model (model A) without such interaction.

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