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Elevated 18:0 lysophosphatidylcholine contributes to the development of pain in tissue injury.

Pain · 2023 · PMC9833116 · PMID 36638307

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While that increase did not reach statistical significance, the context of 18:0 LPC's significant elevation in animal studies, the significant increase of precursor levels in humans, and the evident transcriptional changes occurring in LPC's metabolic enzymes post burn motivated us to further investigate the role of 18:0 LPC in pain. 3.4.

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