5f ), although these differences did not reach statistical significance due to the high temporal variation of this phenotype.
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OxPhos defects cause hypermetabolism and reduce lifespan in cells and in patients with mitochondrial diseases.
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The sentences
On the other hand, the Oligo treatment targeting the complex V did cause a marginally significant (−28%) reduction in coupling efficiency and punctual elevations in proton leak across the lifespan (Fig. 3g, h ).