Occurrence of variants of unknown clinical significance in genetic testing for hereditary breast and ovarian cancer syndrome and Lynch syndrome: a literature review and analytical observational retrospective cohort study.

BMC Med Genomics · 2023 · PMC9843935 · PMID 36647026

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a clear trendno p-value reported

Discussion Implications on our findings concerning HBOC Consistant to other publications [ 61 , 62 ], we can see a clear trend towards ordering larger panels for HBOC at our clinic over the last decade.

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