a significant trendp = 0.052
A significant trend in the discovery cohort ( p = 0.052, standardized beta coefficient = 0.593) and a significant result in the replication cohort ( p = 0.007, standardized beta coefficient = 0.413) were found. 4.
A significant trend in the discovery cohort ( p = 0.052, standardized beta coefficient = 0.593) and a significant result in the replication cohort ( p = 0.007, standardized beta coefficient = 0.413) were found. 4.