Potential Role of ROS in Butyrate- and Dietary Fiber-Mediated Growth Inhibition and Modulation of Cell Cycle-, Apoptosis- and Antioxidant-Relevant Proteins in LT97 Colon Adenoma and HT29 Colon Carcinoma Cells.

Treatment of LT97 cells with increasing concentrations of butyrate resulted in increased p21 protein expression levels (up to 2.3 ± 1.7-fold, 4 mM butyrate), which did not reach statistical significance due to large standard deviations ( Figure 4 D).

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