We then validated these findings using qRT-PCR, observing statistically significant increases in transcription of Mx1 , Oas1 , Oas2 , and a near-significant increase in Oas3 in brain tissue nearing terminal disease (day 9) ( Figure 4 A).
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<i>Orientia tsutsugamushi</i> Infection Stimulates Syk-Dependent Responses and Innate Cytosolic Defenses in Macrophages.
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