Fecal and Tissue Microbiota Are Associated with Tumor T-Cell Infiltration and Mesenteric Lymph Node Involvement in Colorectal Cancer.

Microbial composition was compared across samples using Bray–Curtis dissimilarity, demonstrating a highly significant difference ( p < 10 −5 ) between feces and tissue ( Figure 1 A).

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However, as there were nominally significant differentially abundant ASVs, we investigated whether they could be used to construct classifiers to predict high vs. low tumor T cell infiltration from fecal samples.

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