Protein Tyrosine Phosphatase 1B Deficiency Improves Glucose Homeostasis in Type 1 Diabetes Treated With Leptin.

Leptin treatment of T1D A-KO mice tended to improve glucose tolerance as measured by GTT compared with that of leptin-treated T1D A-WT mice, although the differences did not reach statistical significance ( Fig. 5 F ).

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