Melatonin or Ramelteon for Delirium Prevention in the Intensive Care Unit: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

J Clin Med · 2023 · PMC9863078 · PMID 36675363

Europe PMC DOI

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The sentences

showed a trendp = 0.09so close (0.05 < p ≤ 0.1)

Secondary Outcomes Days of MV: Four RCTs, reporting data on 989 patients, showed a trend in favor of treatment with melatonin with a lower number of days spent on MV (MD −2.80 (95%CI −6.06, 0.47), p = 0.09; I 2 = 94%; Supplementary Materials ).

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