Differential Replication and Cytokine Response between Vaccine and Very Virulent Marek's Disease Viruses in Spleens and Bursas during Latency and Reactivation.

Viruses · 2022 · PMC9864003 · PMID 36680047

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The results of the study indicated that the expression of IFN-γ in the two lymphoid organs was upregulated by MDV infection, and the vv strain MDV/RB1B induced stronger IFN-γ transcriptional upregulation than MDV/CVI988 at 7, 14, and 21 dpi, which showed a trend similar to that reported by Bavananthasivam et al.

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