In a highly significant model (R2 adjusted 0.796, p : 0.0001), progressive patients, both PP at diagnosis and progressive over time (SP and PP) with a higher EDSS at baseline, were at higher risk of accumulating disability over time ( Supplementary Materials Table S4 ).
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Early Predictors of Disability and Cognition in Multiple Sclerosis Patients: A Long-Term Retrospective Analysis.
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Patients exposed to DMT at any time and/or with DMT at T1 showed a trend of lower disability, and EDSS was statistically lower in patients with DMT at T1 ( p : 0.049).