Therapeutic beta-lactam dosages and broad-spectrum antibiotics are associated with reductions in microbial richness and diversity in persons with cystic fibrosis.

Sci Rep · 2023 · PMC9867719 · PMID 36681756

Europe PMC DOI

hedged sentence

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

approached significancep = 0.060so close (0.05 < p ≤ 0.1)

When using the multivariate model as described for alpha diversity above, the impact of beta-lactam PK remained non-significant ( p = 0.411), and the impact of antibiotic spectrum still approached significance ( p = 0.060).

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